However, CB2, particularly in peripheral tissues in the body, is a therapeutic target for treatment of inflammation, pain, atherosclerosis, and osteoporosis (Gertsch, 2008; Gertsch et al., 2008). 

https://www.sciencedirect.com/science/article/abs/pii/B978012802147700053X

https://www.sciencedirect.com/topics/medicine-and-dentistry/caryophyllene